Still waiting for a large RCT to be published to confirm hospital use; however, it is now the only antibody product available to use in people with COVID-19 and high-risk who are immunosuppressed--especially if vaccine non-responders/pts with B cell disorders. However, many trials used the agent too late (e.g., RECOVERY, others) in hospitalized patients for there to be a chance of helping patients in later phases of infection. Convalescent plasma works best as an antiviral. Current FDA EUA for both outpatients and hospitalized patients now enforces the use of high-titer plasma but is only available for immunosuppressed populations. Best used if within three days of illness onset or the first three days of hospitalization. Now indicated only for immunosuppressed populations. High titer units from people who have recovered from COVID-19 and who have been immunized appear to generate the best titers and activity against known circulating variants, including Omicron. An outpatient study of early plasma administration showed a 54% reduction in hospitalization, demonstrating that high-titer units have a role if used early rather than late (in hospital) for average, high-risk patients[4].
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108 HISTORY OF PHILOSOPHY John Wisdom, Paradox and Discovery. New York: Philosophical Library (published in Great Britain by Basil Blackwell), 1965. Pp. ix - 166. $7.50. A collection of pieces in Wisdom's inimitable style, some short reviews and comments, others of address length. The title article and "Metamorphosis of Metaphysics" are the most ambitious, but add little to "Philosophy, Metaphysics and Psychoanalysis". Similarly, the essay "The Logic of God" is the essay "Gods" adapted to a radio audience. Still, John Wisdom writes post-Wittgensteinian philosophy with wit and charm, and without the feeling that it is all terribly academic and dreadfully serious, and in that sense, even the essays he has plagiarized from himself are refreshing. --A. R. L. Jerrold J. Katz, The Philosophy o/Language. New York: Harper & Row, 1966. Pp. xiii [iii] W 326. Studies in Language. $7,25. Mr. Katz tells us that a theory of language exists that combines the virtues of the logical empiricist's formal theory of language structure with the ordinary language philosopher's attention to the facts of language use. The new theory, he says, allows us to predict the indefinite number of sentences proper to a natural language from the finite number of rules for the construction of sentences provided by the theory. It is odd that the rules remind one so of that old-fashioned grammar school business of diagramming sentences. It is also odd that, like the grammar school method, Katz' method introduces the logical features of every new sentence intuitively. This makes it appear as if we must know a proper sentence of a language when we hear one, and the theory does nothing more than engage in a scientific charade on the basis of knowledge acquired in other ways. It is odd, too, that the application to philosophical problems, supposedly cleared up by the theory, are treated much in the way that any philosopher would treat them, except perhaps that the treatment here is more superficial. Finally, it is especially odd that a man who claims to have found rules for the generation of well-formed sentences should generate such unwieldy sentences in his own book. --A.R.L. Booxs R.cFU Castafieda, Hector-Neri, ed., Intentionality, Minds and Perception: Discussions on Contemporary Philosophy. A. Symposium. Detroit: Wayne State University Press, 1967. Pp. 402. $7.95. Faivre, Antoine, Kirehberger vt l'Illuminisrne du dix-huiti$me si$ele. The Hague: Martinus Nijhoff, 1966. Pp. xxx - 284. International Archives of the History of Ideas, 16. Gld. 42.75. Filosofia e In]ormazione. A collection of articles by P. Filiasi Careano, V. Somenzi, E. Paci, G. Derossi, M. Nasti, and S. Ceccato. Padova: Cedam, 1967. Pp. 151 [ii]. Archivio di Filosofia, 1967:1. Paper. Holton, Gerald, ed., Science and Culture: A Study of Cohesive and Disjunctive Forces. Boston : Beacon Press, 1967. Pp. xxxiii - 348. The Daedalus Library, BP 250. (With the exception of two essays, the articles in this book first appeared, several of them in somewhat different form, in the Winter 1965 issue of Daedalus, the Journal of the American Academy of Arts and Sciences.) Paper, $2.45. Hook, Sidney, ed., John Dewey: Philosopher of Science and Freedom. A Symposium. New York: Barnes & Noble, 1967. Pp. vi + 383. (This symposium was arranged in celebration of Dewey's 90th birthday on October 20, 1949. This edition is an unrevised republication of the work first published by Dial Press in 1950.) $9.50. Horosz, William, Escape #om Destiny: Self-Directive Theory of Man and Culture. Springfield , Illinois: Charles C Thomas, 1967. Pp. xv 290. A Monograph in The Bannerstone Division of American Lectures in Philosophy, American Lecture Series, 666. $10.50. Humbert, Jean, Socrate et les Petits Socratiques. Paris: Presses Universitaires de France, 1967. Pp. i -b 293. Paper. Hutin, Serge, Henry More: Essai sur les doctrines theosophiques chez les Platoniciens de Cambridge, Hildesheim: Germany: George Olms, 1966. Pp. 214. Studien und Materialen zur Geschichte der Philosophie, Band 2. Kapleau, Philip, ed., The Three Pillars o] Zen: Teaching, Practice, and Enlightenment. With Trans., Introductions, and Notes by the Editor. Foreward by Huston Smith. Boston: Beacon Press, 1967. Pp: xix [i] - 363. Beacon Paperbacks, 242.* Paper, $2.45. *(This is a... 2ff7e9595c
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